[Sticky] Does PGS Work  

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27/06/2018 6:33 pm  

We will be starting our IVF cycle at Create. Our problem is low sperm count and quality. They have pitched PGS to us. But does PGS really help improve success? 

The have also asked us to do the embryo video monitoring. I believe this is where they video the cell growth 24/7 inside the incubator.

Do these 2 procedures really help success??? 


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(@admin)
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27/06/2018 6:35 pm  

PGS will let both you & your RE know that you are transferring a genetically normal embryo. I am a huge proponent as it eliminates non-viable embryos and the potential heartache of a miscarriage from an aneuploid embryo.

As for the camera monitoring...I have no personal experience with this but would simply say it would allow them to monitor for "normal" development...i.e. Cells are neither developing too quickly or too slowly. This being said...it would be my personal opinion that if you're doing PGS the camera is irrelevant. However someone with more experience on this topic may be able to either correct me or offer a more robust point of view.

Best wishes! 


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27/06/2018 6:36 pm  

Chiming in here, but this may lead to further confusion as the answer may not be as clear cut.

 

Overall in the big scheme of things, the chances of success with and without PGS are the same. The previous thought was that the PGS abnormal embryos that implanted would eventually lead to a miscarriage, or a child born with deformities. However, there is new research showing that PGS testing is not as clear cut. There have been instances where some abnormality (the degree of chromosomal abnormality has not been clear on this), could self-correct and result in a healthy baby.

 

When we started our journey, we were all for PGS testing, as in our eyes we would not be transferring embryos that in the end would result in a loss. However, looking back, and with the new developments in hand, I think it is not a clear cut call any more.

 

If your question came from a place of will I be guaranteed a healthy baby if I do PGS testing? The answer is no. There are so many checkpoints before you as a first time IVFer: will you stimulate well, well they be able to retrieve a good number of eggs, how will they fertilize, how will they develop, how will your lining be... Even if you get to the point of having a blast to transfer and your lining is good, no matter how your blastocyst is graded and even if it is PGS normal, there is still no guarantee that it will implant and grow into a baby.

 

I don't want to depress you, just give you the reality. I know when I came into this process I thought that IVF was the solution to me finally having a baby. Luckily for some it is on the first try, but definitely not for all.

 

Oh and about the embryoscope, the 24 hour/day video, most labs use this as a standard practice. Although it may not increase the chance of a baby in your arms, because it is a tool they are used to using, you may have a hard time pushing back on that one.


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